> ## Content Index > Fetch the complete content index at: https://www.europeans.today/llms.txt > Use this file to discover other available public pages before exploring further. # AstraZeneca’s COVID vaccine withdrawn – Right to the end it was the victim of misinformation - URL: https://www.europeans.today/2024/05/11/astrazenecas-covid-vaccine-withdrawn-right-to-the-end-it-was-the-victim-of-misinformation/ - Published: 2024-05-11T00:20:00.000Z - Updated: 2024-06-08T07:22:06.000Z - Description: AstraZeneca withdrawing its COVID vaccine from the market has nothing to do with blood clots. - Author: Dr Michael Head - Tags: COVID-19, Analysis, AstraZeneca, COVID-19 & Misinformation, COVID-19 Vaccines, COVID-19 & Blood Clot, COVID-19 Infections, COVID-19 Pandemic, Disinformation, Health, Moderna, mRNA Vaccines, Pfizer, Public Health, United Kingdom, Vaccine Adverse Events T he Oxford-AstraZeneca vaccine was a critical part of the COVID-19 pandemic response. However, on May 7 2024, [the European Commission](https://ec.europa.eu/health/documents/community-register/2024/20240327162288/dec%5F162288%5Fen.pdf?ref=europeans.today) announced the vaccine is no longer authorised for use. This EU announcement was preceded by an [application](https://ec.europa.eu/health/documents/community-register/2024/20240327162288/dec%5F162288%5Fen.pdf?ref=europeans.today) from AstraZeneca on March 27 2024 to withdraw the EU marketing authorisation. This development has been covered in various [media outlets](https://www.ndtv.com/world-news/astrazeneca-withdraws-covid-vaccine-globally-cites-commercial-reasons-report-5613955?ref=europeans.today) as primarily related to the known “adverse events”, namely a [very small risk](https://theconversation.com/why-some-people-got-blood-clots-after-the-astrazeneca-vaccine-new-clues-211949?ref=europeans.today) of blood clots. However, other factors are far more likely to be driving this decision. The first AstraZeneca vaccine dose, outside of clinical trials, was [administered](https://www.gov.uk/government/news/one-year-anniversary-of-uk-deploying-oxford-astrazeneca-vaccine?ref=europeans.today) on January 4 2021\. In that year, about **2.5 billion** doses were administered, and an [estimated](https://www.ox.ac.uk/news/2022-07-15-oxford-vaccine-saved-most-lives-its-first-year-rollout?ref=europeans.today) **6.3 million** lives saved. It was a key product at the peak of the pandemic. This includes during the emergence of the delta variant in India, across the first half of 2021 where, amid significant global supply issues, the AstraZeneca vaccine was one of the few tools available during that [humanitarian crisis](https://theconversation.com/covid-19-in-india-an-unfolding-humanitarian-crisis-159654?ref=europeans.today). This COVID vaccine, like those from Pfizer, Moderna, Novavax and others, went through the appropriate levels of testing. The [phase 3 trials](https://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2820%2932661-1/fulltext?ref=europeans.today) (where the vaccine is tested on thousands of people) showed the AstraZeneca product was safe and effective. It was distributed in many countries in Europe in early 2021, including the UK. The potential adverse events related to blood clots were publicly reported in February 2021, with, for example, the UK government and the drugs regulator (the MHRA) then publishing a [statement](https://www.gov.uk/government/news/uk-regulator-confirms-that-people-should-continue-to-receive-the-covid-19-vaccine-astrazeneca?ref=europeans.today) about its continued use on March 18 2021. Amid speculation and investigation, the [European Medicines Agency](https://www.ema.europa.eu/en/news/astrazenecas-covid-19-vaccine-ema-finds-possible-link-very-rare-cases-unusual-blood-clots-low-blood-platelets?ref=europeans.today) and the [World Health Organization](https://www.who.int/news/item/17-03-2021-who-statement-on-astrazeneca-covid-19-vaccine-safety-signals?ref=europeans.today) both highlighted how the benefits of the vaccine greatly outweighed any possible risks. This was a time when COVID levels were extremely high, and getting higher, with around [**4 million**](https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---31-march-2021?ref=europeans.today) confirmed new cases globally per week. It is well established that COVID itself caused a significantly increased risk of these related blood clots and also thrombocytopenia (low platelet count). An August 2021, [analysis](https://www.bmj.com/content/374/bmj.n1931?ref=europeans.today) of **30 million** vaccinated people in the UK showed that the risks of thrombocytopenic events were much higher following a COVID infection, compared with any COVID-related vaccine. From that study, the British Heart Foundation [describe](https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/coronavirus-and-your-health/astrazeneca-covid-vaccine?ref=europeans.today#astraclot) how **for every 10 million** people who are vaccinated with AstraZeneca, there are **66** extra cases of blood clots in the veins and **7** extra cases of a rare type of blood clot in the brain. By comparisons, infection with COVID is estimated to cause **12,614** extra cases of blood clots in the veins and **20** cases of rare blood clots in the brain. To put this into some perspective, these vaccine-associated blood clot rates are much lower than many widely prescribed medicines. For example, the [combined contraception pill](https://www.nhs.uk/contraception/methods-of-contraception/combined-pill/side-effects/?ref=europeans.today), prescribed widely to women, has blood clot-related risks of around **one in 1,000**. With women taking postmenopausal hormone therapy, around [one in 300 per year](https://www.stoptheclot.org/learn%5Fmore/womens%5Fhealth%5Ffaq/?ref=europeans.today) are likely to develop a blood clot. ### **Poor public profile** The AstraZeneca vaccine did suffer from a poor public profile, arguably much of it undeserved. There was some poor quality [reporting](https://www.bmj.com/content/372/bmj.n414?ref=europeans.today) in Germany in January 2021, with claims that the vaccine was only “8% effective in the elderly”. This claim was widely repeated, but it turns out that **8%** figure referred to the percentage of people aged over 65 years in the study and not the efficacy measure. The antivaccine lobby had a field day with fuelling the [“infodemic”](https://www.nhs.uk/contraception/methods-of-contraception/combined-pill/side-effects/?ref=europeans.today), including other false claims such as fabricated links between the vaccine and female infertility. As with the blood clots, COVID infection is known to increase the [risks of infertility](https://academic.oup.com/aje/advance-article/doi/10.1093/aje/kwac011/6511811?ref=europeans.today), but there is no link between infertility and the vaccine. For individuals and families likely to have been injured by any medicine, including any of the COVID vaccines, compensation schemes are available. Many claimants [report](https://theconversation.com/andrew-bridgen-how-anti-vaccine-misinformation-hampers-the-conversation-about-genuine-vaccine-injuries-197351?ref=europeans.today) difficulties and frustrations with accessing the compensation. This is an area where the government-led schemes should be more transparent, and also where the misinformation from the anti-vaccine lobby hinders those groups they are claiming to support. So, why would AstraZeneca withdraw this high-profile product? One reason for the withdrawal is likely to be that other COVID vaccines, such as Pfizer and Moderna, are essentially better products. AstraZeneca is very good, but the mRNA versions [have better](https://www.yalemedicine.org/news/covid-19-vaccine-comparison?ref=europeans.today) effectiveness and safety levels. The initial [concerns](https://theconversation.com/pfizers-ultra-cold-vaccine-could-be-difficult-to-distribute-149848?ref=europeans.today) around the difficulties of the specialist refrigeration needed to transport and store the Pfizer and Moderna vaccines have been overcome, including in low-income countries. The mRNA vaccines are also [easier](https://www.pennmedicine.org/mrna?ref=europeans.today) to update when new variants emerge. With those factors, orders for the AstraZeneca vaccine are probably much lower now than they were in previous years. It is being overlooked in favour of better-performing vaccines. For the Oxford AstraZeneca vaccine, perhaps its time has indeed passed. But it has been a safe and effective vaccine and a key part of the pandemic response for most countries around the world. ![PUBLIC SQUARE UK](https://storage.ghost.io/c/15/40/1540bec0-7154-4feb-b8e1-97f579155b08/content/images/2021/09/end-flat-1.png "PUBLIC SQUARE UK") --- ### **Sources:** ##### ▪ This piece was originally published in [The Conversation](https://theconversation.com/astrazenecas-covid-vaccine-withdrawn-right-to-the-end-it-was-the-victim-of-misinformation-229653?ref=europeans.today) and re-published in PUBLIC SQUARE UK on 13 May 2024\. | The author writes in a personal capacity. ##### ▪ **Cover:** Unsplash/[Hakan Nural](https://unsplash.com/@hakannural?ref=europeans.today). (Licensed under a [Creative Commons Attribution-ShareAlike 4.0 International License](http://creativecommons.org/licenses/by-sa/4.0/?ref=europeans.today).) ![Creative Commons License](https://i.creativecommons.org/l/by-sa/4.0/88x31.png "Cover photograph license") --- ![The Conversation](https://counter.theconversation.com/content/229653/count.gif?distributor=republish-lightbox-basic)